Abstract by Praneeth Hettikankanange
Chemistry and Biochemistry
Qualitative and Quantitative Characterization of Sticky Paper Spray Ionization for Analysis of Analytes in Powder Form
Paper spray ionization (PSI) is a soft ionization technique with many applications in the mass spectrometric analysis of complex solutions including blood, urine, illicit substances, cosmetics, and foodstuffs. PSI technique has been becoming popular among scientists in diverse fields due to inherent characteristics such as low cost, simplicity, rapid detection, and higher efficiency.
Most research teams have focused on optimization of PSI techniques for the analytes in the liquid phase. However, we hypothesize that PSI can also be applied to ionize analytes in the solid phase. MS analysis of solid analytes which has been spread over a surface in a micro or nano level is still a challenge. We are developing a version of PS in which the paper is coated with an adhesive, allowing collection of particulate analytes. The research includes quantitative characterization of sticky PS for analytes in powder form. This approach is of particular interest in forensic analysis and could be used to obtain and analyze individual grains of compounds or mixtures