Abstract by Fischer Summers
Physics and Astronomy
Using a 3D printed device with an antibiotic to remove bacteria from blood for rapid sepsis diagnosis
Sepsis is a condition that takes the lives of 8 million people a year, more than prostate cancer, breast cancer, and AIDS combined. The current techniques for diagnosing sepsis can take days to confirm, and each hour treatment is delayed the mortality rate rises 8%. Rapid sepsis diagnosis is crucial to saving lives. We are developing a small 3D printed device that has bacteria binding antibiotic molecules attached to its surface to pull bacteria out of infected blood where it can be identified quicker. We have attached an antibiotic to a flat 3D printed surface, using XPS to verify binding, and are currently working on a process for removing fluorescent E. coli GFP bacteria from a phosphate buffered saline solution using a 3D printed filter device. Preliminary data shows fluorescence from bacteria caught in the device and right now were are trying to find a way to quantify the amount of bacteria we catch, either with concentration measurement or counting the bacteria.