BYU

Abstract by Nicholas A. Franks

Personal Infomation


Presenter's Name

Nicholas A. Franks

Degree Level

Undergraduate

Co-Authors

Jonard Corpuz Valdoz
Connor J. Knight

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

Pam Van Ry

Title

Tracking metastasis in novel 3D lung model

Abstract

Metastatic cancers contribute to 90% of cancer-related deaths worldwide. Metastatic cancers depend on the migration or invasion of cancer towards the underlying tissues. Here, we created a lung cancer metastasis model. We observed organ-level hallmark of metastasis such as the invasion of cancer towards the vasculature. Or model also showed metastatic progression in terms of expression of pro-metastatic markers, Snail and N-Cadherin. In summary, we engineered a lung model capable of imaging cancer metastasis.