Abstract by Kendell White
Chemistry and Biochemistry
Anti-glycan vaccines against Streptococcus pneumoniae
Bacteria and fungi have gradually become more resistant to modern antibiotics, to solve this problem, development of new types of vaccines has become an alternative way to battle against these lethal microorganisms. We are currently creating a vaccine that uses conjugation of oligosaccharide from Streptococcus pneumoniae that are combined with carefully chosen carrier Qb particle and an NKT cell agonist adjuvant which generate high affinity and longer lasting antibodies. Allowing the body to fight against antibiotic resistant bacteria. These vaccines will not only function well for healthy patients but should also help at risk patients by activating better T cell and B cell response and secondly giving an increase in the affinity to antigen and lasting antibodies.