Abstract by Peter Fullmer

Personal Infomation

Presenter's Name

Peter Fullmer

Degree Level



Isaac Smith
Nathan Steele

Abstract Infomation


Chemistry and Biochemistry

Faculty Advisor

Merritt Andrus


Chiral Acetamide Utilization


In the process of synthesizing Nocardioazine A, a potent anti-cancer drug, a particular acetamide substrate is utilized. This acetamide, with a chiral auxiliary group attached, has potential to be used in a number of other stereospecific reactions. Currently, we have been studying its effectiveness as the dieneophile in a Diels-Alder reaction with a variety of diene substrates. Based on our tests, this reaction has proven to work efficiently, with yields of nearly 90%. The product of these reactions has the potential to then be reduced to extremely unique amino acids, which could then be utilized for a number of other biological applications.