Abstract by Trevan Asay
Chemistry and Biochemistry
Determination of Perfluoroalkyl Carboxylic Acid Concentrations
Perfluoroalkyl carboxylic acids are used as surfactants in many manufacturing processes and have recently been discovered in local groundwater. New techniques are being created to detect and quantify perfluoroalkyl carboxylic acids, one of which is ion chromatography (IC). My research focuses on synthesizing a molecule to be used in IC column material to separate perfluoroalkyl carboxylic acids. I begin the synthesis with 1,2-phenylenediamine. Through several synthetic steps, the molecule is given different functional groups such as acid and anhydride groups. In the next to the last step, the anhydride is reacted with arginine ester in acetic anhydride to make the amino acid derivative. The final step in the synthesis will be to attach the molecule to a resorcinarene, after this step, column material will be made. The positive charge on the guanidine group should bind to the perfluoroalkyl carboxylic acids and allow successful detection by ion chromatography. My presentation will highlight the synthetic procedure used to make the new molecule.