BYU

Abstract by Kyle Gassaway

Personal Infomation


Presenter's Name

Kyle Gassaway

Degree Level

Undergraduate

Co-Authors

Kelton Forson
Nathan Lyons

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

David Michaelis

Title

Exploring the Abilities of a Boron-Templated Cascade Reaction

Abstract

We have discovered a new boron templated cascade reaction which cyclizes allylic alcohols without expensive, toxic metal catalysts. This product can be easily hydrolyzed to give a diol product seen in natural products such as wutaienin. Upon optimization and examining the substrates tolerated by the reaction, we found that the reaction gave good to moderate yields for varying aromatic allylic alcohols. Current research focuses on an enantioselective approach using a chiral boron compound.