BYU

Abstract by Concordia Lo

Personal Infomation


Presenter's Name

Concordia Lo

Co-Presenters

None

Degree Level

Doctorate

Co-Authors

None

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

Steven Castle

Title

Microwave Promoted Iminyl Radical Fragmentations for the Synthesis of Functionalized Nitriles

Abstract

A variety of functionalized nitriles are synthesized by microwave promoted fragmentations of cyclic O-phenyl oxime ethers. Different radical traps were utilized to generate diverse products containing C-O, C-C, C-N, or C-X bonds. Notable advantages of this method include short reaction times, compatibility with 5 membered rings, and absence of metal catalysts or toxic initiators. The application of this procedure was demonstrated by the ring-distortion of estrone.