BYU

Abstract by Erika Weir

Personal Infomation


Presenter's Name

Erika Weir

Co-Presenters

None

Degree Level

Undergraduate

Co-Authors

None

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

David Michaelis

Title

Proximity-enabled dual catalysis on a bifunctional helical peptide catalyst

Abstract

Our laboratory has demonstrated that multifunctional helical peptides can enable enzyme-like reactivity by scaffolding multiple catalysts in close proximity. This scaffolding effect can enable new dual catalytic processes by catalytically generating two reactive intermediates in close proximity on the peptide scaffold.  In this report, we will describe our efforts to develop new dual catalytic processes that take advantage of the helical scaffold to enable proximity-driven reactivity and selectivity.