BYU

Abstract by Concordia Lo

Personal Infomation


Presenter's Name

Concordia Lo

Co-Presenters

None

Degree Level

Doctorate

Co-Authors

Mary Jackman
Siyeon Im
Seth Bohman
Amanda Garrity
Steven Castle

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

Steven Castle

Title

Microwave Promoted Iminyl Radical Fragmentations for the Synthesis of Functionalized Nitriles

Abstract

A variety of functionalized nitriles are synthesized by microwave promoted fragmentations of cyclic O-phenyl oxime ethers. Different radical traps were utilized to generate diverse products containing C-O, C-C, C-N, or C-X bonds. Notable advantages of this method include short reaction times, compatibility with 5 membered rings, and absence of metal catalysts or toxic initiators. The application of this procedure was demonstrated by the ring-distortion of estrone.