Abstract by Joshua Daum
Chemistry and Biochemistry
Chiral recognition using resorcinarenes
Cavitand’s are molecules capable of attracting and encapsulating guest compounds. As such, they have been widely used in the field of supramolecular chemistry to aid in filtration. Recently it has also been discovered that some amino-cavitand compounds have differing binding strengths to enantiomers. Previously our group has synthesized resorcinarenes containing glutamic acid as arms. We have been attempting to replace that arm with a larger functional group such as phenyl in order to increase its selectivity for chiral recognition. We are currently in the process of synthesizing the resorcinarenes and will eventually test our product with UV-vis spectroscopy and NMR spectroscopy. I will present on the progress we have made in synthesizing out resorcinarenes.