Abstract by Samuel Dailey
Identifying Trends in Contraction of Collagen Lattice Model
Human skin is supported by of a network of collagen strands called the extracellular matrix. We model this as a collagen lattice. Fibroblast cells interact with these lattices and are responsible for the contraction that takes place when skin is wounded. Creating a working model of the behavior of collagen lattices in wound contraction is a priority in mathematical biology because of the insights it would offer into wound care and scar prevention.
This research group has built a model of the lattice by randomly placing nodes in the domain and connecting those nodes with spring. This specific research project is focused on identifying the behavior and trends of the model when the connectivity and connection length of the lattice are varied.