BYU

Abstract by Kelton Forson

Personal Infomation


Presenter's Name

Kelton Forson

Degree Level

Doctorate

Co-Authors

Hadi Nazari
Erin Martinez
Kyle Gassaway
Nathan Lyons

Abstract Infomation


Department

Chemistry and Biochemistry

Faculty Advisor

David Michaelis

Title

Boron templated cyclization of allylic alcohols

Abstract

We have discovered a new boron templated cascade reaction which acts on allylic alcohols to cyclize without expensive, toxic metal catalysts. This product can be easily hydrolyzed to give a diol product seen in natural products such as wutaienin. Upon optimization and examining the substrates tolerated by the reaction it was found that the reaction gave good to moderate yields for varying aromatic and non-aromatic allylic alcohols. Current research focuses on an enantioselective approach using a chiral boron compound.